Food

Decanoic acid (MCT, ketogenic diet)

Dietary factor.

In practice

It depends on the case; there is no single guideline.

Effect by goal · level of evidence

Drug-resistant epilepsy

improves Low study (A)

In rat hippocampal slices, decanoic acid (an MCT that rises with the ketogenic diet), but NOT ketone bodies, curbed epileptic activity by inhibiting glutamate AMPA receptors. It explains part of the antiepileptic effect of the keto diet. Ex vivo mechanism.

View the study (study) →

In depth

Diet · Highest evidence: Low · 1 finding

Findings

Resistant epilepsy — improves (Low, study). In rat hippocampal slices, decanoic acid (an MCT that rises with the ketogenic diet), but NOT ketone bodies, curbed epileptic activity by inhibiting AMPA glutamate receptors. Explains part of the antiepileptic effect of the keto diet. Ex vivo mechanism. 26608744

Information, not medical advice. Prescription drugs require a doctor.

Information, not medical advice. Scientific evidence reflects the quality of the studies.