It depends on the case; there is no single guideline.
Effect by goal · level of evidence
Digestion and tolerance
no clear effectLow-moderatestudy (A)
Study: the human gut microbiota does NOT ferment erythritol, which is also absorbed in the small intestine and excreted in urine, and does not harm teeth. This is why it is usually better tolerated than other polyols (less gas). (Note: recent studies have raised doubts about erythritol and cardiovascular risk, separate from this digestive point.)
Digestion and tolerance — no clear effect (Low-moderate, study). Study: the human gut microbiota does NOT ferment erythritol, which is also absorbed in the small intestine and excreted in the urine, and does not harm teeth. For that reason it is usually better tolerated than other polyols (less gas). (Note: recent studies have raised questions about erythritol and cardiovascular risk, separate from this digestive point.) 16277764
Information, not medical advice. Prescription drugs require a doctor.
Information, not medical advice. Scientific evidence reflects the quality of the studies.