Prescription drug

Evolocumab (anti-PCSK9)

Prescription drug.

How to take it

There is no established standard dose for this case; it is advisable to consult a professional.

Safety

Prescription drug (injectable).

Effect by goal · level of evidence

Cholesterol and cardiovascular events

reduces Very high study (A)

60%

FOURIER trial (27,564 patients already on a statin): evolocumab lowered LDL ~60% and reduced cardiovascular events. Confirms that lowering LDL further with an anti-PCSK9 prevents heart attacks and strokes. Injectable prescription drug.

View the study (study) →

In depth

Drug · Highest evidence: Very high · 1 finding

⚠️ Prescription drug (injectable).

Findings

Cholesterol and cardiovascular events — reduces (Very high, study). FOURIER trial (27,564 patients already on a statin): evolocumab lowered LDL by ~60% and reduced cardiovascular events. Confirms that lowering LDL further with an anti-PCSK9 prevents heart attacks and strokes. Injectable prescription drug. 28304224

Information, not medical advice. Prescription drugs require a doctor.

Information, not medical advice. Scientific evidence reflects the quality of the studies.