It depends on the case; there is no single guideline.
Effect by goal · level of evidence
Glucose rise after a meal
reducesModeratemeta-analysis (AAA)
Meta-analysis: small doses (≤30 g) of fructose or its epimers (allulose, tagatose, sorbose) added to a meal with carbohydrates reduce the subsequent glucose rise ('catalytic effect'). Interesting for smoothing out sugar spikes.
Post-meal glucose rise — reduces (Moderate, meta-analysis). Meta-analysis: small doses (≤30 g) of fructose or its epimers (allulose, tagatose, sorbose) added to a carbohydrate-containing meal reduce the subsequent glucose rise ('catalytic effect'). Interesting for smoothing out sugar spikes. 32220498
Information, not medical advice. Prescription drugs require a doctor.
Information, not medical advice. Scientific evidence reflects the quality of the studies.