It depends on the case; there is no single guideline.
Effect by goal · level of evidence
Circulating AGEs (cardiovascular risk)
reducesLowstudy (A)
12-week lifestyle modification program in middle-aged non-diabetic women: serum AGEs (CML, pentosidine) fell compared with control. Small sample; intermediate markers, not clinical outcomes.
Circulating AGEs (cardiovascular risk) — reduces (Low, study). A 12-week lifestyle modification program in non-diabetic middle-aged women: serum AGEs (CML, pentosidine) fell compared with the control group. Small sample; intermediate markers, not clinical outcomes. 19478714
Information, not medical advice. Prescription drugs require a doctor.
Information, not medical advice. Scientific evidence reflects the quality of the studies.