It depends on the case; there is no single guideline.
Effect by goal · level of evidence
Prevention of type 2 diabetes
reducesVery highstudy (A)
7%
Landmark trial (DPP, 3,234 people with prediabetes): a lifestyle change program (7% weight loss and exercise) reduced the onset of diabetes by 58%, more than metformin (31%). Lifestyle outperforms the drug for preventing diabetes.
Lifestyle · Highest evidence: Very high · 1 finding
Findings
Type 2 diabetes prevention — reduces (Very high, study). Landmark trial (DPP, 3,234 people with prediabetes): a lifestyle change program (7% weight loss and exercise) reduced the onset of diabetes by 58%, more than metformin (31%). Lifestyle outperforms the drug for preventing diabetes. 11832527
Information, not medical advice. Prescription drugs require a doctor.
Information, not medical advice. Scientific evidence reflects the quality of the studies.