It depends on the case; there is no single guideline.
Effect by goal · level of evidence
IGF-1, cancer, and mortality
associationLow-moderatestudy (A)
75%
Study in people (with confirmation in mice): between ages 50-65, a high-protein diet was associated with 75% higher mortality and 4 times more cancer death (attenuated if the protein was plant-based). In people over 65, high protein was associated with LOWER mortality. 'Optimal' protein depends on age. Observational.
IGF-1, cancer, and mortality — association (Low-moderate, study). Study in people (with confirmation in mice): between ages 50-65, a high-protein diet was associated with 75% higher mortality and 4 times more cancer death (attenuated if the protein was plant-based). In people over 65, high protein was associated with LOWER mortality. The "optimal" protein depends on age. Observational. 24606898
Information, not medical advice. Prescription drugs require a doctor.
Information, not medical advice. Scientific evidence reflects the quality of the studies.