Supplement

Resveratrol / pterostilbene

Supplement.

How to take it

There is no established standard dose for this case; it is advisable to consult a professional.

Safety

In vitro finding; caution with high doses of resveratrol.

Effect by goal · level of evidence

DNA replicative stress (cautionary signal)

harms Low study (A)

Genetic screening in human cells: resveratrol (and its analog pterostilbene) causes stress in DNA replication, similar to a drug that depletes nucleotides (hydroxyurea). An in vitro finding that tempers the enthusiasm: at certain doses it is not harmless. No clinical outcome.

View the study (study) →

In depth

Supplement · Highest evidence: Low · 1 finding

⚠️ In vitro finding; caution with high doses of resveratrol.

Findings

Replicative DNA stress (caution signal) — harms (Low, study). Genetic screen in human cells: resveratrol (and its analog pterostilbene) causes stress in DNA replication, similar to a nucleotide-depleting drug (hydroxyurea). An in vitro finding that tempers the enthusiasm: at certain doses it is not harmless. No clinical outcome. 32755594

Information, not medical advice. Prescription drugs require a doctor.

Information, not medical advice. Scientific evidence reflects the quality of the studies.