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Supplement

Senolytics (dasatinib + quercetin)

Supplement.
Category
Scientific evidence
Low
Number of findings
1
Sources
Our own summaries · Cited studies

How to take it

There is no established standard dose for this case; it is advisable to consult a professional.

Safety

Preclinical; dasatinib is a prescription drug.

Effect by goal · level of evidence

Senescent cells and pulmonary fibrosis (preclinical)

improves Low study (A)

In mice, the senolytic combination of dasatinib + quercetin eliminated 'zombie' (senescent) cells whose secretome promotes pulmonary fibrosis, improving the disease. Basis of the interest in quercetin as a senolytic for aging; preclinical, with no equivalent clinical proof.

View the study (study) →

In depth

Supplement · Highest evidence: Low · 1 finding

⚠️ Preclinical; dasatinib is a prescription drug.

Findings

  • Senescent cells and pulmonary fibrosis (preclinical) — improves (Low, study). In mice, the senolytic combination of dasatinib + quercetin eliminated 'zombie' (senescent) cells whose secretome promotes pulmonary fibrosis, improving the disease. Basis of the interest in quercetin as a senolytic for aging; preclinical, with no equivalent clinical proof. 28230051

Information, not medical advice. Prescription drugs require a doctor.

Information, not medical advice. Scientific evidence reflects the quality of the studies.

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