It depends on the case; there is no single guideline.
Small study (20 people, no control group): several toxic elements appeared in sweat, some more than in blood or urine. It suggests that sweating eliminates some metals, but it does NOT show that it meaningfully reduces the body's burden: the idea of 'sweating to detoxify' is heavily oversold.
View the study (study) →Lifestyle · Highest evidence: Low · 1 finding
Information, not medical advice. Prescription drugs require a doctor.
Information, not medical advice. Scientific evidence reflects the quality of the studies.