Supplement

Topical retinoids (retinol, tretinoin)

Supplement.

How to take it

There is no established standard dose for this case; it is advisable to consult a professional.

Safety

Initial irritation; oral retinoids are contraindicated in pregnancy.

Effect by goal · level of evidence

Skin photoaging

improves Moderate study (A)

Review: topical retinoids partially reverse sun damage to the skin (wrinkles, spots, sagging) by stimulating collagen and renewing the epidermis. Among the best-supported cosmetic actives; they may irritate at first.

View the study (study) →

In depth

Supplement · Highest evidence: Moderate · 1 finding

⚠️ Initial irritation; oral retinoids are contraindicated in pregnancy.

Findings

Skin photoaging — improves (Moderate, study). Review: topical retinoids partially reverse sun damage to the skin (wrinkles, spots, sagging) by stimulating collagen and renewing the epidermis. Among the best-supported cosmetic actives; they may irritate at first. 39128883

Information, not medical advice. Prescription drugs require a doctor.

Information, not medical advice. Scientific evidence reflects the quality of the studies.