Prescription drug

TRIIM protocol (growth hormone + DHEA + metformin)

Prescription drug.

How to take it

There is no established standard dose for this case; it is advisable to consult a professional.

Safety

Prescription drugs; experimental protocol, not replicated.

Effect by goal · level of evidence

Epigenetic age and immune system

improves Low study (A)

Pioneering study (9 men, no control group): a protocol to regenerate the thymus over one year improved immune markers and reduced estimated epigenetic age by ~2.5 years. Very striking but preliminary: few participants, no control and prescription drugs.

View the study (study) →

In depth

Drug · Highest evidence: Low · 1 finding

⚠️ Prescription drugs; experimental, unreplicated protocol.

Findings

Epigenetic age and immune system — improves (Low, study). Pioneering study (9 men, no control group): a protocol to regenerate the thymus over one year improved immune markers and reduced estimated epigenetic age by ~2.5 years. Very striking but preliminary: few participants, no control, and prescription drugs. 31496122

Information, not medical advice. Prescription drugs require a doctor.

Information, not medical advice. Scientific evidence reflects the quality of the studies.