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Eye health

Eye health and the preservation of vision throughout life have a documented nutritional component that is stronger than popular culture tends to acknowledge: age-related macular degeneration (AMD) is the leading cause of legal blindness… Read more.

8 factors with evidence, ordered from highest to lowest effectiveness. Information, not medical advice.

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In depth

⏱ 3 min read

Eye health and the preservation of vision throughout life have a documented nutritional component that is stronger than popular culture usually acknowledges: age-related macular degeneration (AMD) is the leading cause of legal blindness in people over 65 in developed countries, cataracts are the leading cause of reversible blindness worldwide, dry eye syndrome affects an enormous proportion of people with intensive screen use, and diabetic retinopathy remains a serious complication of diabetes. Several nutritional interventions have robust support in these conditions.

Age-related macular degeneration (AMD)

The nutritional intervention with the best clinical support in ophthalmology: the AREDS2 trial (2013) showed that in people with intermediate AMD, supplementation with a specific formula (lutein 10 mg + zeaxanthin 2 mg + vitamin C 500 mg + vitamin E 400 IU + zinc 80 mg + copper 2 mg) significantly reduces progression to advanced AMD. It is especially effective in people with a low baseline dietary intake of lutein/zeaxanthin.

Recommendations for prevention and management: - Dietary lutein and zeaxanthin: dark leafy green vegetables (spinach, kale), egg yolk, corn; optionally supplementation. - Omega-3 EPA/DHA: adequate intake is associated with lower incidence. - Don't smoke: tobacco is a major risk factor for AMD. - Sun protection (UV): glasses with adequate UV protection. - Mediterranean diet: support in cohorts. - Management of cardiovascular factors: hypertension, diabetes.

Cataracts

The lens becomes progressively cloudy with age; cataracts are treatable with highly effective surgery. For prevention and delay: - Adequate dietary vitamin C: associated with lower risk in cohorts. - Lutein and zeaxanthin: modest support. - Sun protection. - Don't smoke. - Diabetes control (cataracts are more common and occur earlier in diabetes).

Dry eye

An extremely prevalent condition in modern societies with intensive screen use. Interventions: - Omega-3 EPA/DHA: clinical support for dry eye, especially with a high EPA concentration. - Artificial tears. - Eyelid hygiene: cleaning the eyelid margins. - Warm compresses: improve meibomian gland function. - Regular screen breaks: the 20-20-20 rule (every 20 minutes, look at something 20 feet / 6 meters away for 20 seconds). - Environmental humidification. - Vitamin A (important if deficient).

Diabetic retinopathy

A serious complication of poorly controlled diabetes. The only things that truly prevent and slow it are strict glycemic control and control of blood pressure and lipids. Some adjunctive nutritional interventions: - Lutein and zeaxanthin. - Pycnogenol, grape seed extract, bilberry: with modest support for retinal microcirculation. - Omega-3. - Antioxidant vitamins (with caveats).

Glaucoma

A neurodegenerative disease of the optic nerve, frequently associated with elevated intraocular pressure but not exclusively. Pharmacological treatment (pressure-lowering drops) or surgery when necessary. Adjunctive interventions with modest support: regular physical exercise (lowers intraocular pressure), avoiding acute high caffeine intake (it can transiently raise pressure).

General eye health

  • Mediterranean diet: rich in lutein, zeaxanthin, vitamin C, vitamin E, omega-3.
  • Don't smoke: the most important risk factor for AMD and early cataracts.
  • Sun protection: glasses with UV protection.
  • Control of blood pressure, glucose, cholesterol.
  • Regular eye exams: starting at age 40-50, and earlier if there are risk factors or complaints.
  • Visual hygiene with screens.
  • Sufficient sleep.

When to see a doctor

Any acute change in vision, significant eye pain, new double vision, scotomas (spots in the visual field), photopsias (flashes of light), new and abundant floaters (eye floaters), or progressive reduction in visual acuity require prompt ophthalmologic evaluation.

The reasonable conclusion

Long-term eye health is maintained with a diet rich in lutein and zeaxanthin (leafy green vegetables, egg yolk), adequate omega-3 intake, not smoking, sun protection, control of cardiovascular factors (especially diabetes and blood pressure), prudent use of screens, and periodic eye exams. Specific supplementation with lutein/zeaxanthin and the AREDS2 formula has support in intermediate AMD. Acute or progressive vision problems require specialized ophthalmologic care.

References

  1. AREDS2 Research Group (2013). Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the AREDS2 randomized clinical trial. JAMA 309, 19. doi:10.1001/jama.2013.4997
  2. Liu, X.H. et al. (2014). Association between lutein and zeaxanthin status and the risk of cataract: a meta-analysis. Nutrients 6, 1. doi:10.3390/nu6010452
  3. Bhargava, R. et al. (2013). A randomized controlled trial of omega-3 fatty acids in dry eye syndrome. Int J Ophthalmol 6, 6. doi:10.3980/j.issn.2222-3959.2013.06.10
  4. Chiu, C.J.; Taylor, A. (2007). Nutritional antioxidants and age-related cataract and maculopathy. Exp Eye Res 84, 2. doi:10.1016/j.exer.2006.05.015
  5. Christen, W.G. et al. (2007). Antioxidants and macular degeneration: the Physicians' Health Study. Arch Ophthalmol 125, 8. doi:10.1001/archopht.125.8.1106
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Eye health

⏱ 3 min read

Eye health and the preservation of vision throughout life have a documented nutritional component that is stronger than popular culture usually acknowledges: age-related macular degeneration (AMD) is the leading cause of legal blindness in people over 65 in developed countries, cataracts are the leading cause of reversible blindness worldwide, dry eye syndrome affects an enormous proportion of people with intensive screen use, and diabetic retinopathy remains a serious complication of diabetes. Several nutritional interventions have robust support in these conditions.

Age-related macular degeneration (AMD)

The nutritional intervention with the best clinical support in ophthalmology: the AREDS2 trial (2013) showed that in people with intermediate AMD, supplementation with a specific formula (lutein 10 mg + zeaxanthin 2 mg + vitamin C 500 mg + vitamin E 400 IU + zinc 80 mg + copper 2 mg) significantly reduces progression to advanced AMD. It is especially effective in people with a low baseline dietary intake of lutein/zeaxanthin.

Recommendations for prevention and management: - Dietary lutein and zeaxanthin: dark leafy green vegetables (spinach, kale), egg yolk, corn; optionally supplementation. - Omega-3 EPA/DHA: adequate intake is associated with lower incidence. - Don't smoke: tobacco is a major risk factor for AMD. - Sun protection (UV): glasses with adequate UV protection. - Mediterranean diet: support in cohorts. - Management of cardiovascular factors: hypertension, diabetes.

Cataracts

The lens becomes progressively cloudy with age; cataracts are treatable with highly effective surgery. For prevention and delay: - Adequate dietary vitamin C: associated with lower risk in cohorts. - Lutein and zeaxanthin: modest support. - Sun protection. - Don't smoke. - Diabetes control (cataracts are more common and occur earlier in diabetes).

Dry eye

An extremely prevalent condition in modern societies with intensive screen use. Interventions: - Omega-3 EPA/DHA: clinical support for dry eye, especially with a high EPA concentration. - Artificial tears. - Eyelid hygiene: cleaning the eyelid margins. - Warm compresses: improve meibomian gland function. - Regular screen breaks: the 20-20-20 rule (every 20 minutes, look at something 20 feet / 6 meters away for 20 seconds). - Environmental humidification. - Vitamin A (important if deficient).

Diabetic retinopathy

A serious complication of poorly controlled diabetes. The only things that truly prevent and slow it are strict glycemic control and control of blood pressure and lipids. Some adjunctive nutritional interventions: - Lutein and zeaxanthin. - Pycnogenol, grape seed extract, bilberry: with modest support for retinal microcirculation. - Omega-3. - Antioxidant vitamins (with caveats).

Glaucoma

A neurodegenerative disease of the optic nerve, frequently associated with elevated intraocular pressure but not exclusively. Pharmacological treatment (pressure-lowering drops) or surgery when necessary. Adjunctive interventions with modest support: regular physical exercise (lowers intraocular pressure), avoiding acute high caffeine intake (it can transiently raise pressure).

General eye health

When to see a doctor

Any acute change in vision, significant eye pain, new double vision, scotomas (spots in the visual field), photopsias (flashes of light), new and abundant floaters (eye floaters), or progressive reduction in visual acuity require prompt ophthalmologic evaluation.

The reasonable conclusion

Long-term eye health is maintained with a diet rich in lutein and zeaxanthin (leafy green vegetables, egg yolk), adequate omega-3 intake, not smoking, sun protection, control of cardiovascular factors (especially diabetes and blood pressure), prudent use of screens, and periodic eye exams. Specific supplementation with lutein/zeaxanthin and the AREDS2 formula has support in intermediate AMD. Acute or progressive vision problems require specialized ophthalmologic care.

References

  1. AREDS2 Research Group (2013). Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the AREDS2 randomized clinical trial. JAMA 309, 19. doi:10.1001/jama.2013.4997
  2. Liu, X.H. et al. (2014). Association between lutein and zeaxanthin status and the risk of cataract: a meta-analysis. Nutrients 6, 1. doi:10.3390/nu6010452
  3. Bhargava, R. et al. (2013). A randomized controlled trial of omega-3 fatty acids in dry eye syndrome. Int J Ophthalmol 6, 6. doi:10.3980/j.issn.2222-3959.2013.06.10
  4. Chiu, C.J.; Taylor, A. (2007). Nutritional antioxidants and age-related cataract and maculopathy. Exp Eye Res 84, 2. doi:10.1016/j.exer.2006.05.015
  5. Christen, W.G. et al. (2007). Antioxidants and macular degeneration: the Physicians' Health Study. Arch Ophthalmol 125, 8. doi:10.1001/archopht.125.8.1106