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Hibiscus

A flower (Hibiscus sabdariffa); its infusion gently lowers blood pressure.
Category
Scientific evidence
Moderate
Number of findings
1
Sources
Our own summaries · Cited studies
Recommended dose and how to use
2–3 cups of infusion a day or equivalent extract.

How to take it

2–3 cups of infusion a day or equivalent extract.

Safety

Well tolerated; may potentiate antihypertensive drugs.

Effect by goal · level of evidence

Lowering blood pressure

improves Moderate meta-analysis (AAA)

Reduces blood pressure

View the study (meta-analysis) →

In depth

⏱ 2 min read

Hibiscus, also called roselle or Jamaica flower, is a tropical plant whose deep red flower is used as an infusion in countless cultures (agua de Jamaica in Mexico, karkadé in Egypt, bissap in West Africa); beyond its refreshing use, over the past twenty years it has established itself as one of the few herbal remedies with consistent clinical evidence for lowering blood pressure, with an excellent safety profile and a minimal cost compared with any pharmacological antihypertensive.

The relevant active compounds are the anthocyanins and polyphenols of the dried calyx, which act through several complementary mechanisms: mild inhibition of angiotensin-converting enzyme (an effect similar to that of pharmacological ACE inhibitors), a mild diuretic effect, modulation of endothelial function via nitric oxide, and a direct antioxidant effect on the vasculature; this multimodal profile explains the robustness of the effect on blood pressure documented in serious clinical trials.

Hypertension: the indication with the best evidence

Several meta-analyses have shown that regular consumption of hibiscus infusion or standardized extract reduces systolic blood pressure by 5 to 7 mmHg and diastolic by 3 to 5 mmHg in people with mild to moderate hypertension, with doses of 1.5-2 grams daily of dried calyx (1-2 cups of a strongly brewed infusion) for 4-8 weeks; the effect is comparable to that of some mild pharmacological antihypertensives as monotherapy.

A classic randomized trial published in the Journal of Nutrition compared hibiscus vs captopril (a standard pharmacological ACE inhibitor) in people with mild hypertension for 4 weeks and found similar efficacy between the two treatments, a surprising result that has been partially replicated in later studies and that places hibiscus as a reasonable first-line option for mild hypertension in people who prefer nutritional interventions before starting drug therapy.

Lipid profile and other uses

On the lipid profile, several trials have shown modest reductions in LDL cholesterol and triglycerides with prolonged use of hibiscus; for blood glucose, the data are weaker but point to small improvements in people with insulin resistance; as for diuretic function, hibiscus maintains a tradition of use in herbal medicine with modest but consistent clinical data supporting its described effect in any European herbal for centuries.

How to take it and precautions

The doses studied range from 1.5 to 3 grams daily of dried calyx (1-2 teaspoons as an infusion 1-2 times a day, letting it steep for 5-10 minutes to extract the anthocyanins well), or the equivalent in standardized dry extract (250-500 mg/day); the effect on blood pressure appears between 2 and 4 weeks and is maintained as long as regular consumption continues.

Generally very well tolerated; adverse effects are rare and mild (digestive discomfort, occasionally headache); people taking antihypertensives may experience an additional drop in blood pressure, and it is advisable to monitor the response to avoid hypotension; those taking hydrochlorothiazide should be cautious because there are data on a pharmacokinetic interaction; it is best avoided in pregnancy (it may have a uterotonic effect), in breastfeeding because of limited data, and in people with baseline hypotension or who take drugs that can lower blood pressure further.

References

  1. McKay, D.L. et al. (2010). Hibiscus sabdariffa L. tea (tisane) lowers blood pressure in prehypertensive and mildly hypertensive adults. J Nutr 140, 2. doi:10.3945/jn.109.115097
  2. Serban, C. et al. (2015). Effect of sour tea (Hibiscus sabdariffa L.) on arterial hypertension: a systematic review and meta-analysis of randomized controlled trials. J Hypertens 33, 6. doi:10.1097/HJH.0000000000000585
  3. Herrera-Arellano, A. et al. (2004). Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension: a controlled and randomized clinical trial. Phytomedicine 11, 5. doi:10.1016/j.phymed.2004.04.001
  4. Hopkins, A.L. et al. (2013). Hibiscus sabdariffa L. in the treatment of hypertension and hyperlipidemia: a comprehensive review of animal and human studies. Fitoterapia 85. doi:10.1016/j.fitote.2013.01.003
  5. Mozaffari-Khosravi, H. et al. (2009). The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes. J Hum Hypertens 23, 1. doi:10.1038/jhh.2008.100

Information, not medical advice. Scientific evidence reflects the quality of the studies.

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